胰岛素抗体

胰岛素抗体

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  • ¥1680
  • YLKBIO
  • YLK-KT2419D
  • 国产/进口
  • 2025年07月12日
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    • 详细信息
    • 技术资料
    • 供应商

      优利科(上海)生命科学有限公司

    • 库存

      100

    • 靶点

      详询

    • 级别

      科研

    • 目录编号

      /

    • 克隆性

      多克隆

    • 抗原来源

      详见说明书

    • 保质期

      1年

    • 抗体英文名

      Anti-Insulin

    • 抗体名

      Insulin抗体

    • 标记物

      详询

    • 宿主

      详询

    • 适应物种

      /

    • 免疫原

      见产品详情

    • 亚型

      IgG

    • 形态

      冻干或液体

    • 应用范围

      见产品详情

    • 保存条件

      -20℃

    • 浓度

      1mg/ml

    • 规格

      详询

    胰岛素抗体
    英文名称  Anti-Insulin 
    中文名称  胰岛素抗体 
    别    名  ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10. 
    浓    度  1mg/1ml 
    规 格  0.1ml/100μg  0.2ml/200μg     
    抗体来源  Rabbit  
    克隆类型  polyclonal 
    交叉反应  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit
    产品类型  一抗    
    研究领域  肿瘤 心血管 细胞生物 神经生物学 信号转导 细胞凋亡 生长因子和激素 糖尿病 内分泌病 新陈代谢  
    胰岛素抗体
    蛋白分子量  predicted molecular weight: 5.77754kDa 
    性    状  Lyophilized or Liquid 
    免 疫 原  KLH conjugated Insulin from porcine pancreas 
    亚    型  IgG 
    纯化方法  affinity purified by Protein A 
    储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 
    产品应用   ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 
    (石蜡切片需做抗原修复) 
     not yet tested in other applications.
     optimal dilutions/concentrations should be determined by the end user.  
    保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
    胰岛素抗体
    Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
    产品介绍 Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.
    Function : Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    Subunit : Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    Subcellular Location : Secreted.
    DISEASE : Hyperproinsulinemia, familial (FHPRI) [MIM:176730]: An autosomal dominant condition characterized by elevated levels of serum proinsulin-like material. Note=The disease is caused by mutations affecting the gene represented in this entry. 
    Diabetes mellitus, insulin-dependent, 2 (IDDM2) [MIM:125852]: A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. Note=The disease is caused by mutations affecting the gene represented in this entry. 
    Diabetes mellitus, permanent neonatal (PNDM) [MIM:606176]: A rare form of diabetes distinct from childhood-onset autoimmune diabetes mellitus type 1. It is characterized by insulin-requiring hyperglycemia that is diagnosed within the first months of life. Permanent neonatal diabetes requires lifelong therapy. Note=The disease is caused by mutations affecting the gene represented in this entry. 
    Maturity-onset diabetes of the young 10 (MODY10) [MIM:613370]: A form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Similarity : Belongs to the insulin family.
    Database links : UniProtKB/Swiss-Prot: P01315.2 pig
    胰岛素(Insulin)是胰岛beta细胞分泌的一种激素,可以减低血糖浓度。此抗体特异性地识别猪胰岛素,并与人的胰岛素有交叉反应,主要用于胰岛细胞瘤的功能性研究。
    胰岛素抗体

     
    Anti-IRS-4  胰岛素受体底物-4抗体
    Anti-ISR(Insulin Receptor)  胰岛素受体抗体
    Anti-ISR-α (Insulin Receptor-α)  胰岛素受体-α抗体
    Anti-ISR-β (Insulin Receptor-β)  胰岛素受体-β抗体
    Anti-ITG-α/ CD49d  整合素α4抗体
    Anti-ITG-β1/CD29(integrin β1)  粘附分子整合素β1抗体
    Anti-ITG-α5/CD49e(Integrin α5)  粘附分子整合素α5抗体
    Anti-ITG-β3/CD61(Integrin β chain,β3 precursor)  整合素-β3抗体
    Anti-JNK1/3 (c-Jun amino-terminal kinase 1/3)  c-Jun氨基末端激酶1/3抗体
    Anti-KATPC (ATP-Sensitive K+ Channel Subunits uKATP-1—ATP)  ATP敏感性钾通道蛋白抗体
    Anti-Ki-67  Ki-67 Antigen抗体
    Anti-Kiss-1 (Metastasis-suppressor KiSS-1 precursor)  肿瘤转移抑制基因抗体
    Anti-Klf4 (Kruppel likefactor 4)  肠道内富含的Kruppel样因子/上皮锌指蛋白抗体

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