万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-IMPDH2
- 抗体名:
IMPDH2抗体
- 标记物:
详询
- 宿主:
详询
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
冻干或液体
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IMPDH2 |
| 中文名称 5'肌苷磷酸脱氢酶2抗体 |
| 别 名 IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPD2; IMPDH 2; IMPDH II; IMPDH-II; Impdh2; IMPDHII; Inosine 5' monophosphate dehydrogenase 2; Inosine-5''-monophosphate dehydrogenase 2; IMDH2_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit |
| 产品类型 一抗 |
研究领域 肿瘤 免疫学 信号转导 生长因子和激素 ![]() |
| 蛋白分子量 predicted molecular weight: 56kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IMPDH2 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. |
| Function : Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. |
| Subunit : Homotetramer. |
| Subcellular Location : Cytoplasm. Nucleus. |
| Tissue Specificity : IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
| Post-translational modifications : The N-terminus is blocked. |
| Similarity : Belongs to the IMPDH/GMPR family. |
Contains 2 CBS domains. ![]() |
| MRP3(Multidrug Resistanec-Associated Protein 3) 多药耐药相关蛋白3(抗原) |
| MRP1(Multidrug Resistanec-Associated Protein 1) 多药耐药相关蛋白1(抗原) |
| LRP/MVP (Lung resistance related protein) 肺耐药相关蛋白(抗原) |
| MSLN(mesothelin) 间皮素(多肽抗原) |
| MSH2 (mutS homolog 2) MSH2抗原 |
| NKR(Neuromedin B Receptor) 神经激肽B受体(抗原) |
| NF-L(Neurofilament triplet L) 低分子量神经丝蛋白(抗原) |
| NF-M (Neurofilament triplet M) 中分子量神经丝蛋白(抗原) |
| NF-H(Neurofilament triplet H) 高分子量神经丝蛋白(抗原) |
| NIS(Na+/I-symporter;NIS) 钠碘转运体蛋白(多肽抗原) |
| NFKBp65(p65 NF-kappa B;p65NFKB) 细胞核因子或称k基因结合核因子(多肽抗原) |
| NR2A (Glutamate receptor2A) 谷氨酸受体(N端抗原) |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Ia抗原 I region-associated antigen
小白鼠的 H- 2基因复合体的 I区基因的产物。 I-A和 I-E亚区产物,在化学方面已研究得很清楚,即糖蛋白,由α肽链(分子量约为 35,000)和β肽链(分子量为 27,000)以非共价键结合而形成一个分子,在 I- A亚区译码为一条α链( Aα)和二条β链 [Aβ, Ae(也称 Eβ) ],在 I- E亚区译码为一条α链。整个是合成 Aα- Aβ和 Eα- Ae二种 Ia抗原。与 H- 2K, D产物( H- 2抗原)不同,只在一定的细胞如 B细胞、 T细胞部分、巨噬
标准曲线绘制及扩增效率计算: 可以在 excel 上进行扩增效率的计算。稀释梯度可以设置为-1 /- 2/-3,每个梯度对应的 CT 值分别为 23.69 / 27.04 / 30.27,如下图,进行标准曲线绘制。通过标准曲线可以得到线性方程(y = -3.29 x + 20.42)与 R2 值(R2 = 0.9999)。将线性方程得到的斜率(-3.29)带入扩增效率计算公式中: 即可得到扩增效率。本基因使用 Vazyme #Q711 扩增效率为 101.35%。 只有当扩增效率满足 90
三句话读懂一篇 CNS:百岁老人的长寿秘诀;雄性激素越高越有
菌群,产生独特的胆汁酸,可能通过抑制肠道病原体生长而促进长寿,提出了控制胆汁酸库可能对延年益寿有益处!图 1:来源站酷海洛2. Nature genetics: 解析组蛋白 H3.3-K27M 致瘤活性的分子机制弥漫性中线胶质瘤(Diffuse midline gliomas,DMGs)是致死力极强的儿童脑肿瘤。2021 年 7 月 26 日,爱尔兰达柏林三一学院 Adrian P. Bracken 研究组联合英国爱丁堡大学 Steven M. Pollard 研究组在 Nature genetics














