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优利科(上海)生命科学有限公司
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1年
Anti-IL-26/AK155
IL-26/AK155抗体
详询
兔
/
见产品详情
IgG
冻干或液体
见产品详情
-20℃
1mg/ml
详询
英文名称 Anti-IL-26/AK155 |
中文名称 白介素26抗体 |
别 名 AK155; IL 26; IL-26; IL26; IL26_HUMAN; Interleukin 26; Interleukin-26; Protein AK155. |
浓 度 1mg/1ml |
规 格 0.2ml/200μg |
抗体来源 Rabbit |
克隆类型 polyclonal |
交叉反应 Human, Dog, Pig, Cow |
产品类型 一抗 |
研究领域 免疫学 |
蛋白分子量 predicted molecular weight: 18kDa |
性 状 Lyophilized or Liquid |
免 疫 原 KLH conjugated synthetic peptide derived from human IL-26 C-terminus |
亚 型 IgG |
纯化方法 affinity purified by Protein A |
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
(石蜡切片需做抗原修复) |
not yet tested in other applications. |
optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq] |
Function : May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. |
Subunit : Homodimer. |
Subcellular Location : Secreted. |
Tissue Specificity : Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). |
Similarity : Belongs to the IL-10 family. |
Database links : UniProtKB/Swiss-Prot: Q9NPH9.1 |
IL-26作为炎性细胞因子,可通过多重效应参与炎症过程。 |
GLP-2(Glucagon-like peptide-2) 胰高血糖素样肽-2(多肽抗原) |
GRP94 (gp96) 94kDa 糖调节蛋白(抗原) |
G Protein(Guanine nucleotide-binding regulatory protein) G蛋白(鸟苷酸结合蛋白)(抗原) |
GR (Glucocorticoid receptor) 糖皮质激素受体 多肽 |
GSK-3β(NT) (Glycogen Synthase Kinase-3β) 糖原合酶激酶-3β(抗原) |
CKR-L2( G protein-coupled receptor-2 ) G蛋白偶联受体-2(抗原) |
GSK-3β, (Glycogen Synthase Kinase-3) 葡萄糖合成激酶-3(抗原) |
GTP-CH-1 三磷酸鸟苷环水解酶(抗原) |
H5N1-M2(Avian influenza Matrix Protein-2) H5N1流感病毒M2型(抗原) |
HCV-Core 丙型肝炎病毒-C区(多肽) |
HCV-NS1 丙型肝炎病毒-NS1(抗原) |
HCV-NS3 丙型肝炎病毒-NS3(抗原) |
HCV-NS4a 丙型肝炎病毒-NS4a(抗原) |
HEV 戊型肝炎病毒(抗原) |
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