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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
96
- 靶点：
/
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-IL-22R
- 抗体名：
IL-22R抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
见产品详情
- 亚型：
IgG
- 形态：
冻干或液体
- 应用范围：
见产品详情
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-IL-22R |
| 中文名称 白介素-22受体抗体 |
| 别 名 Interleukin-22 receptor subunit alpha-1; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22RA1; CRF2-9; IL22R; IL22R1; I22R1_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig |
| 产品类型 一抗 |
研究领域 免疫学  |
| 蛋白分子量 predicted molecular weight: 61kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IL-22R N-terminus |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 The receptor for IL22 is a new member of the class II cytokine receptor family. IL22 Receptor forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL22 and its receptor activate the JAK/STAT signaling pathway. IL22 Receptor is expressed in normal liver and kidney and their cell lines HepG2 and TK10. A soluble form of IL22 Receptor, also termed IL22 binding protein (IL22BP) and IL22 receptor alpha 2 (IL22 RA2), was identified very recently. IL22BP prevents binding of IL22 to the functional cell surface IL22 Receptor complex and neutralizes IL22 activity. LPS induces IL22 expression, which indicates the role of IL22 in inflammatory response. |
| Function : Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| Subunit : Heterodimer with IL10RB and with IL20RB. |
| Subcellular Location : Membrane; Single-pass type I membrane protein. |
| Tissue Specificity : Expressed in kidney, liver and lung. |
| Similarity : Belongs to the type II cytokine receptor family. |
| Contains 2 fibronectin type-III domains. |
Database links : UniProtKB/Swiss-Prot: Q8N6P7.1 |
| ECG2 (sophagus cancer-related gene-2) 食道癌相关基因（抗原） |
| fgL2 (Fibrinogen-like 2) 凝血酶原酶 (又称：纤维介素蛋白；前凝血素) |
| FLIP S/L （Flice-like Inhibitory Protein） 凋亡调节基因之一（抗原） |
| FoxP3 叉头蛋白3-T细胞转录因子（多肽抗原） |
| GAD-65 (glutamate decarboxylase) 谷氨酸脱羧酶-65(抗原) |
| GAP-43 ( Growth associated protein-43 ) 生长相关蛋白-43（抗原） |
| Gastrin 胃泌素（抗原） |
| GFAP（Glial Fibrillary Acidic Protein） 胶质纤维酸性蛋白（抗原） |
| MMP-1(matrix metalloproteinases-1) 基质金属蛋白酶-1（抗原） |
| MMP-2(Collagenase IV /Gelatinase A/Metallo proteinase-2) 基质金属蛋白酶-2(多肽抗原) |
| MMP-3(matrix metalloproteinase-3/Transin-1/SL-1/Stromelysin-1 precursor) 基质金属蛋白酶-3(抗原) |
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文献和实验上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人白介素-22 (IL-22)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 IL-22 单抗包被于酶标板上，标准品和样品中的 IL-22与单抗结合，加入生物素化的抗人 IL
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 豚鼠白介素-22 (IL-22)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗豚鼠 IL-22 单抗包被于酶标板上，标准品和样品中的 IL-22与单抗结合，加入生物素化的抗豚鼠 IL
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 小鼠白介素-22 (IL-22)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗小鼠 IL-22 单抗包被于酶标板上，标准品和样品中的 IL-22与单抗结合，加入生物素化的抗小鼠
