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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-Integrin alpha 5/CD49e/ITGA5
- 抗体名:
Integrin alpha 5/CD49e/ITGA5抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-Integrin alpha 5/CD49e/ITGA5 |
| 中文名称 整合素α5抗体Integrin α5 |
| 别 名 Alpha 5 beta 1; CD49 antigen-like family member E; CD49e; ECMRVI; Fibronectin Receptor alpha; Fibronectin receptor alpha subunit; Fibronectin receptor, alpha subunit; FNR; FNRA; gpIc/IIa; Integrin alpha 5 (fibronectin receptor alpha); Integrin alpha 5; Integrin alpha F; Integrin alpha-5; Integrin alpha-F; Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Very late Activation Antigen 5; Very Late Activation Protein 5 alpha; Very late activation protein 5, alpha subunit; VLA5; VLA5A; ITA5_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Pig, Cow, Horse |
| 产品类型 一抗 |
研究领域 细胞生物 免疫学 信号转导 干细胞 细胞粘附分子 ![]() |
| 蛋白分子量 predicted molecular weight: 110kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Integrin alpha 5 C-terminus |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Integrin alpha 5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell surface mediated signaling. |
| Function : CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling. |
| Subunit : Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. Interacts with HIV-1 Tat. |
| Subcellular Location : Membrane; Single-pass type I membrane protein. |
| Similarity : Belongs to the integrin alpha chain family. |
| Contains 7 FG-GAP repeats. |
| Database links : UniProtKB/Swiss-Prot: P08648.2 |
ITG-α5粘附分子整合素α5也是细胞粘附分子的超家族成员,广泛分布于细胞表面和细胞外基质的糖蛋白,不仅介导细胞与细胞或细胞与基质之间的连接,而且参与细胞间的信号转导,细胞的生长移行,肿瘤的转移浸润,免疫炎性反应,血管生成等一系列的生理和病理过程。![]() |
| VEGF(Vascular endothelial growth factor) 血管内皮生长因子(多肽片断抗原) |
| ZCWCC1(Zinc finger CW-type coiled-coil domain protein 1) ZCWCC1抗原 |
| CD105/Endoglin/TGF-β receptor CD105/转化生长因子β受体抗原 |
| CD44 CD44抗原 |
| CD56/NCAM1(Neural Cell Adhesion Molecule 1) 神经细胞粘附分子1抗原 |
| CD86/B7-2 CD86抗原 |
| CDK5(Cyclin Dependent Kinase 5) 周期素依赖性激酶5抗原 |
| CK2(Cytokeratin 2) 酪氨酸激酶2抗原 |
| c-Myc tag c-Myc tag标签蛋白 |
| CNP/CNPase ( 2',3'-cyclic-nucleotide 3'-phosphodiesterase) C型钠尿肽抗原 |
| CNTF(Ciliary Neurotrophic Factor) 睫状神经营养因子抗原 |
| Collagen Ⅳ(Anti-Collagen Type Ⅳ) IV型胶原抗体(Collagen Ⅳ Ⅳ 型胶原) |
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