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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
100
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-IL-6
- 抗体名：
IL-6抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
见产品详情
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
见产品详情
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-IL-6 |
| 中文名称 白介素6抗体 |
| 别 名 Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmacytoma growth factor; IFNB2; IL 6; IL6 protein; Interferon beta 2; Interleukin 6 (interferon beta 2); Interleukin 6; Interleukin6; IL6_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Mouse, Rat |
| 产品类型 一抗 |
研究领域 免疫学  |
| 蛋白分子量 predicted molecular weight: 23kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-6 (111-150aa) |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
| 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]. |
| Function : Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. |
| Subcellular Location : Secreted. |
| Post-translational modifications : N- and O-glycosylated. |
| DISEASE : Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis. |
| Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men. |
| Similarity : Belongs to the IL-6 superfamily. |
| Database links : UniProtKB/Swiss-Prot: P05231.1 (human) |
| UniProtKB/Swiss-Prot: P08505.1 (mouse) |
| 生长因子和激素（ Growth Factor and Hormones） |
| 白介素-6是一种多功能细胞因子，既可由淋巴细胞产生，也能由非淋巴细胞合成。在体内免疫反应调节、血细胞的增生、防御机制和急性期反应中起重要作用。 |
IL6是一种糖蛋白，它既可诱导急性期时相关蛋白的产生，也是β细胞终末分化并分泌抗体的必需因子。 |
| Anti-MAG-a/L-MAG (Myelin associated glycoprotein) 髓鞘相关糖蛋白-a抗体 |
| Anti-MAGE-1/HLA-A1 protein (melanoma antigen family A member 1) 黑素瘤抗原-1抗体 |
| Anti-MAPKK1 (MAP kinase kinase 1) 丝裂原活化蛋白激酶激酶1 |
| Anti-MAPKK2 (MAP kinase kinase 2) 丝裂原活化蛋白激酶激酶2抗体 |
| Anti-Maspin (mammary serine protease inhibitor) 抑癌基因抗体 |
| Anti-Matriptase 蛋白裂解酶（一种新的癌基因）抗体 |
| Anti-MBP (Myelin Basic Protein, MBP) 髓鞘碱性蛋白抗体 |
| Anti-MCP-1 (monocyte chemotactic protein1) 巨噬细胞趋化蛋白-1抗体 |
| Anti-M-CSF (Macrophage Colony Stimulating Factors) 巨噬细胞克隆刺激因子抗体 |
| Anti-MDM2 (urine double minute 2) 双微体2癌基因抗体 |
| Anti-Megsin/SER—PINB7 丝氨酸(或半胱氨酸)蛋白酶抑制剂B7抗体 |
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白介素6抗体
￥1280 - 1980
