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优利科(上海)生命科学有限公司
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1年
Anti-IGF 1
IGF 1抗体
详询
兔
/
见产品详情
IgG
Lyophilized or Liquid
见产品详情
-20℃
1mg/ml
详询
英文名称 Anti-IGF 1 |
中文名称 胰岛素样生长因子1抗体 |
别 名 IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1R_HUMAN. |
浓 度 1mg/1ml |
规 格 0.1ml/100μg 0.2ml/200μg 1ml/1mg |
抗体来源 Rabbit |
克隆类型 polyclonal |
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep |
产品类型 一抗 |
研究领域 免疫学 发育生物学 信号转导 生长因子和激素 糖尿病 |
蛋白分子量 predicted molecular weight: 7.7kDa |
性 状 Lyophilized or Liquid |
免 疫 原 KLH conjugated synthetic peptide derived from human IGF-1(72-95aa) |
亚 型 IgG |
纯化方法 affinity purified by Protein A |
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
产品应用 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
(石蜡切片需做抗原修复) |
not yet tested in other applications. |
optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth. |
Function : The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. |
Subcellular Location : Secreted. |
DISEASE : Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. |
Similarity : Belongs to the insulin family. |
Database links : |
Entrez Gene: 281848 Cow |
Entrez Gene: 3480 Human |
Entrez Gene: 16001 Mouse |
Entrez Gene: 25718 Rat |
Omim: 147370 Human |
胰岛素样生长因子1(IGF-1)是一种生长调节激素,由肝分泌并入血液循环的中性多肽,具有调节生长和代谢、胰岛素样及促细胞分裂的活性,主要作用于成人。 |
NT-3 神经生长因子-3(抗原) |
NT-4,NT-5 神经生长因子4/5(抗原) |
NTN (Neurturin) 神经生长因子(抗原) |
Nurr1 核受体相关因子-1(抗原) |
CD73 (5´-nucleotidase cytosolicⅡ) 胞浆-5´-核苷酸酶-Ⅱ 抗原 |
OGP (Ostegenic Growth Peptide) 成骨生长肽 (骨生长激素肽)(多肽) |
OPN 骨桥蛋白(多肽抗原) |
P53 肿瘤抑制基因(抗原) |
PACAP-27/38 腺苷酸环化酶激活肽-27/38(抗原) |
PACAP-38 腺苷酸环化酶激活肽-38(抗原) |
PACAP/VIP receptor 腺苷酸环化酶激活肽/血管活性肠肽受体(抗原) |
PACAP receptor-I 腺苷酸环化酶激活肽受体(抗原) |
PADI4 (HL-60 PAD)(Protein-arginine deiminase type IV,PADI 4,PAD I4 ) 关节炎相关基因 |
PDGF-A 血小板源性生长因子-1(抗原) |
PDGF-B 血小板源性生长因子-B(抗原) |
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