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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-IRX4
- 抗体名:
IRX4抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
KLH conjugated synthetic peptide derived from human IRX4
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IRX4 |
| 中文名称 Iroquois同源蛋白4抗体 |
| 别 名 Homeodomain protein IRXA3; Iroquois Homeobox Protein 4; Iroquois-class homeodomain protein IRX-4; Iroquoisclass homeodomain protein IRX4; Irx4; IRX4_HUMAN; IRXA3. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse |
| 产品类型 一抗 |
研究领域 心血管 发育生物学 表观遗传学 ![]() |
| 蛋白分子量 predicted molecular weight: 57kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IRX4 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 The Iroquois homeobox gene family of transcription factors regulate aspects of embryonic development including anterior/posterior and dorsal/ventral axis patterning in the central nervous system. The Iroquois family are clustered on two loci, IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes Irx1, Irx2 and Irx4; the IRXB group is comprised of Irx3, Irx5 and Irx6. Irx1 and Irx2 are both widely expressed during development in the lung epithelium and also in the ventricular septum. Irx1 and Irx2 also play a role in digit formation (E11.5–E14.5). The Irx gene family members are each expressed in a distinct pattern during mouse heart development. Specifically, Irx1 and Irx2 are expressed in the ventricular septum and Irx3 is expressed in the ventricular trabeculated myocardium. In addition, Irx4 is expressed in the linear heart tube and the AV canal, and Irx5 is expressed in the endocardium lining the ventricular and atrial myocardium. Furthermore, the IRX4 gene may modulate cardiac development and function. Although the heart of Irx4(-) mice appears to develop normally, adult Irx4(-) mice exhibit cardiomyopathy, including cardiac hypertrophy and decreased contractility. |
| Function : Likely to be an important mediator of ventricular differentiation during cardiac development. |
| Subcellular Location : Nucleus. |
| Tissue Specificity : Predominantly expressed in cardiac ventricles. |
| Similarity : Belongs to the TALE/IRO homeobox family. |
Contains 1 homeobox DNA-binding domain.![]() |
| BYTA1(Breast cancer susceptbility gene 1)(human) 乳腺癌易感基因1抗原(人) |
| PSD-95 突触后密度蛋白95(抗原) |
| PTP-1B (Protein-tyrosine phosphatase, non-receptor ) 蛋白酪氨酸磷酸酶-1B(抗原) |
| RAR-α (Retinoic acid -R-α) 维甲酸受体-α 多肽 |
| glycoprotein (E1 glycoprotein) [Rubella virus] 风疹病毒糖蛋白多肽片段 |
| SAP (Synapse associated protein- I) 突触相关蛋白-1(抗原) |
| SARS S-protein(抗原) |
| SARS putative orflab polyprotein (SARS coronavirus CUHK-W1)(抗原) |
| Secretin 分泌素(抗原) |
| Secretin receptor 分泌素受体(抗原) |
| Socs 1 (suppressor of cytokine signaling 1) 细胞激酶信号-1抑制剂(抗原) |
| SM-MHC(Cardiac myosin heavy chain) 心肌肌凝蛋白多肽 |
| α-Synuclein 核突触蛋白(抗原) |
| α-Synuclein 核突触蛋白(抗原) |
| SuYTtance P Receptor (Neurokinin receptor1;Tachykinin receptor1) P物质受体(抗原) |
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