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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
/
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-Islet 2
- 抗体名:
Islet 2抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
KLH conjugated synthetic peptide derived from human Islet 2
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-Islet 2 |
| 中文名称 胰岛素基因增强结合蛋白2抗体 |
| 别 名 Insulin gene enhancer protein ISL 2; Insulin gene enhancer protein ISL-2; Insulin gene enhancer protein ISL2; ISL 2; ISL 2 transcription factor; ISL 2 transcription factor LIM/homeodomain; ISL2; ISL2 transcription factor; ISL2 transcription factor LIM/homeodomain; ISL2_HUMAN; Islet-2; Islet2; FLJ10160. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep |
| 产品类型 一抗 |
研究领域 细胞生物 发育生物学 神经生物学 信号转导 ![]() |
| 蛋白分子量 predicted molecular weight: 40kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Islet 2 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2. Islet-2 is a nuclear protein that contains two N-terminal LIM domains, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus. Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways. Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates. Somatic, but not visceral, motor neurons maintain Islet-2 expression at later embryonic stages. An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character. Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character. |
| Function : Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. |
| Subcellular Location : Nucleus. |
| Similarity : Contains 1 homeobox DNA-binding domain. |
| Contains 2 LIM zinc-binding domains. |
Database links : UniProtKB/Swiss-Prot: Q96A47.1![]() |
| Apaf-1 (Apoptosis protease activating factor-1)(CT) 凋亡蛋白活性因子-1(抗原) |
| Apaf-1 (Apoptosis protease activating factor-1)(NT) 凋亡蛋白活性因子-1(抗原) |
| AR (Androgen Receptor) 雄激素受体(抗原) |
| AT (Angiotenogen) 血管紧张素原(抗原) |
| Apo-E (Apolipoprotein E) 载脂蛋白E(抗原) |
| IKI3 family protein |
| ILK-1 (Integrin-linked protein kinase 1) 整合素连接激酶-1 |
| Aromatase 芳香化酶(抗原) |
| ART(Artemin)(抗原) |
| AQP-2 (aquaporin Protein-2) 水通道蛋白-2(抗原) |
| BACE( ASP2 ) β分泌酶(抗原) |
| Bassoon(YTN) |
| Bax (Bcl-2 Assaciated X protein) Bax(多肽抗原) |
| Bcl-2(抗原) Bcl-2(多肽抗原) |
| BDNF (Brain-derived Neurotrophin factor) 脑源神经营养因子(脑衍化神经营养因子) |
| bFGF 碱性成纤维细胞生长因子(多肽抗原) |
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