- ￥1280 - 1980
- YLKBIO
- YLK-KT2168D
- 国产/进口
- 2025年07月14日
- WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 兔
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- 详细信息
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
100
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
/
- 保质期：
1年
- 抗体英文名：
Anti-IF3/Mitocondrial Translational Initiation Factor 3
- 抗体名：
IF3/Mitocondrial Translational Initiation Factor 3抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
KLH conjugated synthetic peptide derived from human Mitocondrial Translational Initiation Factor 3
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-IF3/Mitocondrial Translational Initiation Factor 3 |
| 中文名称 线粒体翻译起始因子3抗体 |
| 别 名 DC38; IF 3; IF 3Mt; IF-3(Mt); IF-3Mt; IF3; IF3(mt); IF3M_HUMAN; IF3Mt; mitochondrial; Mt; MTIF3; Translation initiation factor IF 3, mitochondrial precursor; Translation initiation factor IF-3. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
| 产品类型 一抗 |
研究领域 细胞生物 神经生物学 表观遗传学 Alzheimer's  |
| 蛋白分子量 predicted molecular weight: 28kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Mitocondrial Translational Initiation Factor 3 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 IF3 is also known as MTIF3 (mitochondrial translational initiation factor 3), DC38, IF3(mt) or IF-3mt, and is a 278 amino acid protein that is localized to mitochondria. IF3 aids in the initiation of protein synthesis by binding the 28S ribosomal subunit, which is a protein synthesis initiation site. The 28S and 39S ribosomal structures are subunits of the 55S ribosome, whose formation is favored in the absence of IF3, because IF3 allows the subunits to remain in their free form. Altered forms of IF3 may affect IF3’s function, which could alter the availability of mitochondrial encoded proteins, leading to oxidative stress and possibly causing an increased susceptibility to Parkinson’s disease. Polymorphism of the gene encoding IF3 is thought to be associated with Parkinson’s disease. |
| Function : IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. |
| Subcellular Location : Mitochondrion. |
| Similarity : Belongs to the IF-3 family. |
Database links : UniProtKB/Swiss-Prot: Q9H2K0.4 |
| NF-H（Neurofilament triplet H) 高分子量神经丝蛋白(抗原) |
| NIS(Na+/I-symporter;NIS) 钠碘转运体蛋白（多肽抗原） |
| NFKBp65(p65 NF-kappa B;p65NFKB) 细胞核因子或称k基因结合核因子(多肽抗原) |
| NR2A （Glutamate receptor2A） 谷氨酸受体（N端抗原） |
| NRP-1（neuropilin-1） 神经纤毛蛋白-1(抗原) |
| NRP-2（neuropilin-2） 神经纤毛蛋白-2（抗原） |
| NSBP1(Nucleosome-binding protein 1) 核小体结合蛋白1(抗原) |
| NTP，Neurual thread protein 神经丝蛋白（抗原） |
| OAT-1 (Organic anion transporter 1)human 阴离子转运蛋白-1(人源） |
| OAT-1 (Organic anion transporter 1)mouse、rat 阴离子转运蛋白-1（大、小鼠同源：人源见YT-0606P） |
| OAT-3(Organic anion transporter 3) 阴离子转运蛋白-3(抗原) |
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线粒体翻译起始因子3抗体
￥1280 - 1980
