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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-INTS3
- 抗体名:
INTS3抗体
- 标记物:
/
- 宿主:
兔
- 适应物种:
/
- 免疫原:
KLH conjugated synthetic peptide derived from human INTS3
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-INTS3 |
| 中文名称 集成复杂蛋白亚单位3抗体 |
| 别 名 Integrator complex subunit 3; C1orf193; C1orf60; FLJ21919; INT 3; INT3; INTS3; SOSS complex subunit A. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Dog, Pig, Cow, Horse, Rabbit |
| 产品类型 一抗 |
研究领域 细胞生物 信号转导 表观遗传学 ![]() |
| 蛋白分子量 predicted molecular weight: 118kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human INTS3 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS3 (integrator complex subunit 3), also known as INT3 or SOSS-A, is a 1,043 amino acid nuclear protein and is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. Expressed in the nucleus, INTS3 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1q21.3. |
| Subunit : Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Component of the SOSS complex, composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80. SOSS complexes containing SOSS-B1/OBFC2B are more abundant than complexes containing SOSS-B2/OBFC2A. Interacts with SOSS-B1/OBFC2B, SOSS-B2/OBFC2A and SOSS-C/C9orf80; the interaction is direct. Interacts with NBN/NBS1. |
| Subcellular Location : Nucleus. Note=Localizes to nuclear foci following DNA damage. |
Similarity : Belongs to the Integrator subunit 3 family.![]() |
| Anti-L-Citrulline (Rabbit Anti-L-Citrulline) 抗L-瓜氨酸抗体 |
| Anti-LDL-R (Low-density lipoprotein receptor precursor) 低密度脂蛋白受体抗体 |
| Anti-Leptin 瘦素抗体 |
| Anti-Leptin 瘦素抗体 |
| Anti-Leptin receptor 瘦素受体抗体 |
| Anti-Leptin receptor(long) 瘦素受体抗体(长) |
| Anti-Leptin receptor(long) 瘦素受体抗体(长) |
| Anti-Lgr5/GPR49 肠上皮干细胞蛋白抗体 |
| Anti-LH (Mouse Anti-Human Luteinizing Hormone Monoclonal Antibody) 鼠抗人促黄体生成素抗体 |
| Anti-L-HDC (L-Histidine decarboxylase) L-组氨酸脱羧酶抗体 hu, mo, rat, bov, dog, pig, chi |
| Anti-LHRH/GNRH (luteinizing hormone-releasing hormone) 黄体激素释放激素抗体/促性腺激素释放激素抗体 |
| Anti-LIF (leukemia inhibitory factor) 白血病抑制因子抗体 |
| Anti-Lingo-1 Nogo受体作用蛋白抗体 |
| Anti-Livin (Inhibitors of apoptosis proterins Livin) 一种新的凋亡抑制蛋白抗体 |
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