- ￥1280 - 1980
- YLKBIO
- YLK-KT2033D
- 国产
- 2025年07月14日
- WB=1:100-500 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 兔
- /
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
100
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-Integrin alpha 2/CD49b
- 抗体名：
Integrin alpha 2/CD49b抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
KLH conjugated synthetic peptide derived from human Integrin alpha 2 C-terminus
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:100-500 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-Integrin alpha 2/CD49b |
| 中文名称 整合素α2抗体 |
| 别 名 Integrin alpha 2; CD49b antigen; BR; CD 49b; CD49 antigen like family member B; CD49b; CD49b; Collagen receptor; DX5 ; Glycoprotein Ia deficiency included; GP Ia; GP Ia deficiency, included; GPIa; HPA 5 included; HPA5 included; Itga2; Platelet alloantigen Br(a), included; Platelet antigen Br; Platelet glycoprotein GPIa; Platelet glycoprotein Ia; Platelet glycoprotein Ia/Iia; Platelet membrane glycoprotein Ia; Platelet receptor for collagen, deficiency of, included; Very late activation protein 2 receptor alpha 2 subunit; VLA 2 alpha chain; VLA 2; VLA 2 subunit alpha; VLA2 alpha chain; ITA2_HUMAN. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit |
产品类型 一抗  |
| 研究领域 细胞生物 |
| 蛋白分子量 predicted molecular weight: 127kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Integrin alpha 2 C-terminus |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. |
| Function : Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. |
| Subunit : Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21. Binds to human echoviruses 1 and 8 capsid proteins and acts as a receptor for these viruses. Interacts (via ITAG2 I-domain) with rotavirus A VP4; this interaction only occurs in rotavirus integrin-dependent strains, for which ITGA2 acts as a receptor. |
| Subcellular Location : Membrane; Single-pass type I membrane protein. |
| Similarity : Belongs to the integrin alpha chain family. |
| Contains 7 FG-GAP repeats. |
| Contains 1 VWFA domain. |
Database links : UniProtKB/Swiss-Prot: P17301.1 |
| Anti-TLR2 (Toll-like receptor 2) Toll样受体2抗体 |
| Anti-TLR4 (Toll-like receptor 4) Toll样受体4抗体 |
| Anti-TLR5/CD285 (Toll-like receptor 5) Toll样受体5抗体 |
| Anti-TM（Thrombomodulin) 血栓调节蛋白抗体 |
| Anti-TmR2（GDNFRβ；TRN-R；GFR-alpha-2；NTNR-2） 胶质细胞系源性神经营养因子受体β抗体 |
| anti-Tn-C(tenascin-C) 腱糖蛋白-C抗体 |
| Anti-TNF-α (Mouse Anti-Human Tumor Necrosis Factor-α Monoclonal Antibody) 鼠抗人肿瘤坏死因子-α单克隆抗体 |
| Anti-TNF-α(Tumor Necrosis Factor-α) 肿瘤坏死因子-α抗体 |
| Anti-TNF-β(Tumor Necrosis Factor-β) 肿瘤坏死因子-β抗体 |
| Anti-TPⅠ （topoisomeraseⅠ） 拓普西异构酶Ⅰ抗体 |
| Anti-DNA TPⅡα (DNA topoisomeraseⅡα) DNA拓普西异构酶Ⅱ抗体 |
| Anti-TPH (Trptophan Hydroxylase) 色氨酸羟化酶抗体 |
| Anti-TPO (Thyroid Peroxidase) 抗甲状腺过氧化物酶抗体 |
| Anti-TRA16 (Testicular orphan nuclear receptor-4 (TR4)-associated protein) 睾丸激素受体相关蛋白16抗体 |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验人整合素α2β1(ITG α2β1)酶联免疫分析（ELISA）
人 整合素α2β1(ITG α2β1) 酶联免疫 分析（ ELISA ） 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 整合素α2β1(ITG α2β1) 的 含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 人 整合素α2β1(ITG α2β1) 水平。用纯化的 整合素α2β1(ITG α2β1) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 整合素
人整合素αVβ3（ITG αⅤβ3）酶联免疫分析（ELISA）
人整合素αVβ3（ITG αⅤβ3） 酶联免疫 分析（ ELISA ） 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 整合素αVβ3（ITG αⅤβ3） 的 含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 人 整合素αV β 3 （ ITG αⅤβ 3 ） 水平。用纯化的抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 整合素αV β 3 （ ITG αⅤ
【参考值】ELISA法：0.8ug/L 【临床意义】 由于在纤溶系统起核心作用的纤溶酶的半衰期仅为0.1秒，不便进行测定，既往用于反映纤溶状态的指标是测定其前身纤溶酶或纤溶酶的抑制物（α2-抗纤溶抑制物），通过两者水平降低，而推断出纤溶活性增强，医学教育|网搜集整理近年来则转而测定纤溶酶-α2抗纤溶酶复合物含量，纤溶酶生成后迅速与α2-抗纤溶酶1：1摩尔形成复合物使纤溶酶灭活，PIC的出现直接反映纤溶酶的生成，在血栓前状态和DIC时增高。
