- ￥1280 - 1980
- YLKBIO
- YLK-KT2029D
- 国产
- 2025年07月14日
- WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 兔
- /
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- 详细信息
- 技术资料
- 供应商：
优利科（上海）生命科学有限公司
- 库存：
100
- 靶点：
详询
- 级别：
科研
- 目录编号：
/
- 克隆性：
多克隆
- 抗原来源：
详见说明书
- 保质期：
1年
- 抗体英文名：
Anti-IL-31
- 抗体名：
IL-31抗体
- 标记物：
详询
- 宿主：
兔
- 适应物种：
/
- 免疫原：
KLH conjugated synthetic peptide derived from human IL-31
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 保存条件：
-20℃
- 浓度：
1mg/ml
- 规格：
详询
| 英文名称 Anti-IL-31 |
| 中文名称 白细胞介素31抗体 |
| 别 名 Interleukin-31; 1700013B14RIK, IL31; interleukin-31 precursor. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
产品类型 一抗  |
| 研究领域 免疫学 |
| 蛋白分子量 predicted molecular weight: 16kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IL-31 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| （石蜡切片需做抗原修复） |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.  |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development. |
| Function : Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. |
| Subcellular Location : Secreted. |
| Tissue Specificity : Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. |
| Database links : UniProtKB/Swiss-Prot: Q6EBC2.1 |
IL-31是一种新型T细胞衍生的细胞因子,其功能受体复合物是由IL-31RA/GPL/GLM R和OSMR组成的异二聚体。它们在过敏性和非过敏性疾病中起重要作用。 |
| Anti-Tubulin-β 微管蛋白（免疫组化用抗体） |
| Anti-Tubulin-β 微管蛋白抗体 |
| Anti-Tubulin-γ 微管蛋白-γ抗体 |
| Anti-TY3H/TH (Tyrosine Hydroxylase ) 酪氨酸羟化酶抗体 |
| Anti-Tyrosinase 酪氨酸酶抗体 |
| Anti-Tβ10 (thymosin β10) 胸腺素β10抗体 |
| Anti-UAT (Urate transporter/channel) 尿酸盐转运子抗体 |
| Anti-VAP1 (vascular adhesion protein 1) 血管粘附蛋白1抗体 |
| Anti-VCAM-1/CD106 (Vascuolar cell adhesion molecule 1) 血管内皮细胞粘附分子抗体 |
| Anti-VEGF(Vascuoar endothelial growth factor) 血管内皮生长因子抗体 |
| Anti-VEGF（Rabbit） 血管内皮生长因子抗体 |
| Anti-VEGFR1/VEGF-R1/Flt-1 （Vascular Epidemal growth factor receptor-1） 血管内皮生长因子受体1抗体 |
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白细胞介素31抗体
￥1280 - 1980
