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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
63
- 靶点:
/
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-Islet-1/2
- 抗体名:
Islet-1/2 抗体
- 标记物:
/
- 宿主:
Human, Mouse, Rat, Cow, Horse, Sheep
- 适应物种:
/
- 免疫原:
KLH conjugated synthetic peptide derived from human Islet-1/2
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/1ml
- 规格:
详询
| 英文名称 Anti-Islet-1/2 |
| 中文名称 胰岛素基因增强结合蛋白1/2抗体 |
| 别 名 Insulin gene enhancer protein ISL 1; Insulin gene enhancer protein ISL-1; Insulin related protein; Isl 1; ISL LIM homeobox 1; ISL1; ISL1 transcription factor LIM homeodomain; ISL1 transcription factor, LIM/homeodomain (islet 1); ISL1 transcription factor, LIM/homeodomain; ISL1_HUMAN; Islet-1; Islet1. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep |
产品类型 一抗 ![]() |
| 研究领域 心血管 细胞生物 神经生物学 信号转导 干细胞 细胞类型标志物 |
| 蛋白分子量 predicted molecular weight: 39kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human Islet-1/2 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Islet-1 and Islet-2 contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events. Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation. In developing mouse teeth, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord. Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner. |
| Function : Binds to one of the cis-acting domain of the insulin gene enhancer. |
| Subcellular Location : Nucleus. |
| Tissue Specificity : Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. |
| Similarity : Contains 1 homeobox DNA-binding domain. |
| Contains 2 LIM zinc-binding domains. |
| Database links : UniProtKB/Swiss-Prot: P61371.1 |
| anti-TCF7L2(transcription factor 7-like 2) 转录因子7类似物2抗体 |
| Anti-TDP-43/TARDBP (tar DNA binding protein) Tar DNA 结合蛋白43抗体 |
| Anti-Tenascin 固生蛋白抗体 |
| Anti-Tenascin/TN 细胞粘合素抗体 |
| Anti-TFF3 (trefoil factor3) 三叶肽因子3抗体 |
| Anti-TFPI-2 (tissue factor pathway in hibitor-2) 组织因子途径抑制剂-2抗体 |
| Anti-TGF-α (Ttansforming Growth Factor –α) 转移生长因子–α抗体 |
| Anti-TGF-β1(Ttansforming Growth Factor –β1) 转移生长因子–β1抗体 |
| Anti-TGF-β2 (Ttansforming Growth Factor –β2) 转移生长因子–β2抗体 |
| Anti-TGF-β3(Ttansforming Growth Factor –β3) 转移生长因子–β3抗体 |
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