Recombinant HCoV-NL63 Nucleocapsid Protein
Catalog #: DRA63 Derived From: E.coli
Description:
Recombinant HCoV-NL63 Nucleocapsid Protein is produced by our E.coli expression system and the target gene encoding Met1-His377 is expressed with a 6His tag at the N-terminus.
Accession: Q6Q1R8
Names(Known as): HCoV-NL63 Nucleocapsid Protein; HCoV-NL63 coronavirus NP Protein; HCoV-NL63 np Protein; HCoV-NL63 novel coronavirus Nucleoprotein Protein
Quality Control:
Mol Mass: 45.9kDa AP Mol Mass: 53kDa, reducing conditions
Purity: Greater than 85% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl,150mM NaCl,50mM Arginine,pH7.5
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Application:
Immunogen, calibrator or standard.
Background:
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY