Recombinant Penaeus aztecus Pen a1
Catalog #: DRA98 Derived From: E.coli
Description:
Recombinant Penaeus aztecus Pen a1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr284 is expressed with a 6His tag at the C-terminus.
Accession: Q3Y8M6
Names(Known as): Tropomyosin Pen a 1.0102; Allergen Pen a 1; Tropomyosin Pen a 1; Pen a 1.0102; Penaeus aztecus Pen a1
Quality Control:
Mol Mass: 33.7kDa AP Mol Mass: 38kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation:
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Application:
Immunogen, calibrator or standard.
Background:
IgE-mediated hypersensitive reactions to ingestion of shellfish are among the most serious forms of food allergies.Pen a 1 from brown shrimp Penaeus aztecus is the only major allergen of shrimp and binds up to 75% of all shrimp-specific IgE antibodies this molecule may be an excellent model for the usage of allergens with reduced IgE antibody-binding capacity for specific immunotherapy.Recombinant Pen a 1 and natural Pen a 1 are structurally and immunologically identical and rPen a 1 may be used as the basis for component-resolved diagnosis and the generation of modified shrimp tropomyosin for allergen-specific immunotherapy.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY