Recombinant Dermatophagoides pteronyssinus Der p 2
Catalog #: DRA117 Derived From: Human Cells
Description:
Recombinant Dermatophagoides pteronyssinus Der p 2 is produced by our Mammalian expression system and the target gene encoding Asp18-Asp146 is expressed with a 6His tag at the C-terminus.
Accession: P49278
Names(Known as): Mite group 2 allergen Der p 2; DERP2; Allergen Der p II; DPX; Der p 2; Dermatophagoides pteronyssinus Der p 2
Quality Control:
Mol Mass: 14.9kDa AP Mol Mass: 16kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Application:
Immunogen, calibrator or standard.
Background:
The Dermatophagoides pteronyssinus group 2 (Der p 2), is one of the most representative HDM allergens and is recognized by more than 90% of HDM-allergic patients. Purified Der p 2 was shown to be efficient to as a prophylactic AIT to prevent type 2 immunity in murine asthma. Recombinant hypoallergenic peptides derived from Der p 2 were described to exhibit less in vivo allergenicity than Der p 2 whole allergen, while preserving immunogenicity. And high prevalences of IgE sensitization to Der p 2 (70–90%) have been reported among mite-allergic patients .
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY