Human IGF-I (诊断原料,肿瘤标志物）

Recombinant Human IGF-I 

 

Catalog #:  DC031        Derived From: E.coli   

 

Description:

Recombinant Human Insulin-Like Growth Factor I/IGF-1(4-70) (RG) is produced by E.coli expression system and the target gene encoding Thr52-Ala118 is expressed.

Accession:  P05019

Names(Known as):Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

 

Quality Control

Mol Mass:  7.3kDa                 AP Mol Mass:  9kDa, reducing conditions

Purity:  Greater than 95% as determined by reducing SDS-PAGE.

 

Formulation:

Supplied as a 0.2 μm filtered solution of 20mM HAc-NaAc, pH 4.5.

 

Shipping:

The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.

 

Storage:

Reconstituted protein solution should be stored at ≤ -20°C.

 

Purification: 
Ion-exchange chromatography.

 

Immunoreactivity: 
N.A.

 

Application:
Immunogen, calibrator or standard.

 

Background:

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.

 

FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY