【参考文献】 1. Baxter RC.1986 The somatomedins: insulin-like growth factors.Adv Clin Chem.25:49-115 2. Daughaday WH, Rotwein P.1989 Insulin-like growth factors l and ll. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev. 10:68-91 3. Spencer EM(Ed.)1991 Modern Concepts of lnsulin-Like Growth Factors. New York:'Elsevier. 4. Klapper DG, Svoboda ME, Van Wyk JJ.1983 Sequence analysis of somatomedin-C:confirmation of identity with insulin-like growth factor-l.Endocrinology.112:2215-2217. 5. Rinderknecht E, Humbel RE.1978 The amino acid sequence of human insulin-like growthfactor l and its structural homology with proinsulin.J Biol Chem. 253:2769-2276. 6. Clemmons DR, Van Wyk JJ.1984 Factors controlling blood concen-tration ofsomatomedin C.Clin Endocrinol Metab.13:113-143. 7. Ballard J, Baxter R, Binoux M, et al.1989 On the nomenclature of the lGF bindingproteins.Acta Endocrinol(Copenh).121:751-752. 8. Drop sLS. 1992 Report on the nomenclature of the lGF binding proteins.J.Clin'Endocrinol Metab.74:1215-1216. 9. Martin JL, Baxter RC. 1986 Insulin-like growth factor binding protein from human plasma.Purification and characterization.J Biol Chem. 261:8754-8760. 10. Binkert C, Landwehr J, Mary JL, Schwander J, Heinrich G. 1989 Cloning, sequenceanalysis and expression of a cDNA encoding a novel insulin-like growth factor bindingprotein (IGFBP-2).EMBO J.8:2497-2502. 11. Furlanetto RW,Underwood LE,Van Wyk JJ, D'Ercole AJ.1977 Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay.J. Clin lnvest.60:648-657. 12. Daughaday WH, Kapadia M,Mariz l.1987 Serum somatomedin binding proteins:physiologic significance and interference in radioligand assay.J Lab Clin Med.109:355-363. 13. Breier BH, Gallaher BW, Gluckman PD.1991 Radioimmunoassay for insulin-like growth factor-l: solutions to some potential problems and pitfalls.J Endocrinol.128:347-357. 14. Daughaday WH,Mariz lK, Blethen SL.1980 Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor andradioimmunoassay of somatomedin in native and acid-ethanol-extracted serum. J ClinEndocrinol Metab.51:781-788. 15. Ranke MB(ed.);: Diagnostics of Endocrine Function in Children and Adolescents,Basel,Karger, 2003,pp 166-199 16. Rosenfeld RG,Wilson DM, Lee PDK, Hintz RL.1986 Insulin-like growth factors l and ll in evaluation of growth retardation.J Pediatr. 109:428-433. 17. Clemmons DR, Van-Wyk JJ, Ridgway EC,Kliman B,Kjellberg RN,Underwood LE.1979 Evaluation of acromegaly by radioimmunoassay of somatomedin-C.N.Engl J Med. 301:1138-1142 18. Zapf J, Walter H, Froesch ER.1981 Radioimmunological determination of insulin-like growth factors land ll in normal subjects and in patients with growth disorders andextrapancreatic tumor hypoglycemia.J Clin Invest.68:1321-1330. 19. Blum WF.1992 Insulin-like growth factors and their binding proteins. In: Ranke MB, ed.Functional Endocrinologic Diagnostics in Children and Adolescence.Mannheim:J+JVerlag; 102-117. 20. Rieu M, Girard F, Bricaire H, Binoux M.1982 The importance of insulin-like growth factor(somatomedin) measurements in the diagnosis and surveillance of acromegaly.J ClinEndocrinol Metab.55:147-153. 21. Blum WF, Ranke MB, Bierich JR.1988 A specific radioimmunoassay for insulin-like growth factor ll: the interference of lGF binding proteins can be blocked by excess IGF-I.Acta Endocrinol (Copenh).118:374-380. 22. Wilson EM, Oh Y, Rosenfeld RG (1997) Generation and characterization of an IGFBP-7 antibody: ldentification of 31 kD IGFBP-7 in human biological fluids and Hs578T humanbreast cancer conditioned media.J Clin Endocrinol Metab Vol 82,4:1301-1303 22. Ranke MB, Schweizer R, Elmlinger MWw, Weber K, Binder G, Schwarze CP, Wollmann HA(2000)Significance of basal IGF-l,IGFBP-3 and IGFBP-2 measurements in thediagnostics of short stature in children. Horm Res 54:60-68 23. Ranke MB, Schweizer R, Elmlinger Mw, Weber K, Binder G, Schwarze CP, Wollmann HA(2001) Relevance of lGF-I, IGFBP-3 and lGFBP-2 measurements during GH treatment of GH-deficient and non-GH-deficient children and adolescents.Horm Res55:155-124 24. Address NIBSC: Blance Lane, South Mimms, Potters Bar, Hertford EN 6 3 QG, Great Britain 25. Burns C,Rigsby P, Moore M, Rafferty B. (2009)The first International Standard for lnsulin-like Growth Factor-1 (IGF-1) for immunoassay: Preparation and calibration in aninternational collaborative study.Growth Hormone & IGF Research (2009) 26. Blum WH, Breier BH (1994)Radioimmunoassays for lGFs and lGFBPs.GrowthRegulation 4 (Suppl.1):11-19 27. Ranke MB,Osterziel KJ, Schweitzer R, Schuett B., Weber K., Robbel P, Vornwald A,Blumenstock G, EImlinger MB (2003)Reference Levels of lnsulin-Like-Growth Factor l inthe Serum of Healthy Adults: Comparison of Four lmmunoassays.Clin Chem Lab MedVol41(10):1329-1334