Narmafotinib,1393653-34-3

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Narmafotinib

CAS No. : 1393653-34-3

MCE 国际站：Narmafotinib

产品活性：Narmafotinib (AMP-945) 是粘着斑激酶 (FAK) 的抑制剂 (K_D=0.21 nM)。Narmafotinib 抑制 MDA-MB-231 细胞中 397Y-FAK 的自磷酸化，IC₅₀=7 nM，具有较低的细胞毒性 (IC₅₀=2.7 μM, MDA-MB-231 细胞)。

研究领域：Protein Tyrosine Kinase/RTK

作用靶点：FAK

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