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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
EGF Receptor Peptide Acetate
- 库存:
10
- 供应商:
TargetMol
- CAS号:
T21723L
- 规格:
2 mg/50 mg/100 mg/1 mg/5 mg/25 mg/1 mL/10 mg
| 规格: | 2 mg | 产品价格: | ¥491.0 |
|---|---|---|---|
| 规格: | 50 mg | 产品价格: | ¥3730.0 |
| 规格: | 100 mg | 产品价格: | ¥5360.0 |
| 规格: | 1 mg | 产品价格: | ¥343.0 |
| 规格: | 5 mg | 产品价格: | ¥997.0 |
| 规格: | 25 mg | 产品价格: | ¥2480.0 |
| 规格: | 1 mL | 产品价格: | ¥2580.0 |
| 规格: | 10 mg | 产品价格: | ¥1760.0 |
Product Introduction
Bioactivity
英文名:EGF Receptor Peptide Acetate
描述:Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK).

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文献和实验EGF受体是一种糖蛋白, 广泛分布于哺乳动物的上皮细胞、人的成纤维细胞、胶质细胞、角质细胞等。EGF 受体是一条含有1186个氨基酸残基的多肽链, 相对分子质量为170kDa,由三个部分组成:①很大的细胞外结构域:约621个氨基酸残基,富含半胱氨酸(51个), 并形成多对二硫键,其上结合有糖基,是EGF结合的位点。②跨膜区∶由23个氨基酸残基组成;③细胞质结构域,由542个氨基酸残基组成,含有无活性的酪氨酸激酶和几个酪氨酸磷酸化的位点。
Assays to Monitor Degradation of the EGF Receptor
to conduct receptor downregulation assays are described. Monitoring of ubiquitination and degradation of the EGFR subsequent to stimulation with the receptor ligand EGF is described. Finally, protocols to quantitatively measure degradation of the EGFR
Motility Signaled From the EGF Receptor and Related Systems
Cell motility is now recognized as central to many biological processes. Growth factors, such as those that activate the epidermal growth factor receptor (EGFR), drive biochemically and biologically distinct subsets of migration critical
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