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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
TMC647055 Choline Hydroxide Salt
- 库存:
10
- 供应商:
TargetMol
- CAS号:
T21537L
- 规格:
10 mg/5 mg/50 mg/1 mg/100 mg/25 mg/1 mL
| 规格: | 10 mg | 产品价格: | ¥2990.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥2160.0 |
| 规格: | 50 mg | 产品价格: | ¥6910.0 |
| 规格: | 1 mg | 产品价格: | ¥996.0 |
| 规格: | 100 mg | 产品价格: | ¥9490.0 |
| 规格: | 25 mg | 产品价格: | ¥4950.0 |
| 规格: | 1 mL | 产品价格: | ¥2850.0 |
Product Introduction
Bioactivity
英文名:TMC647055 Choline Hydroxide Salt
描述:TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)>20 μM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro biochemical, kinetic, and virological profile that is currently undergoing clinical evaluation.

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文献和实验Purification Scheme for Ubiquitin Expression Lysate
ammonium acetate, pH 5.1). Buffer B is usually the high salt buffer (0.5 M ammonium acetate, pH 5.1). When you adject the pH, be sure to always use either ammonium hydroxide (NH4 OH) or acetic acid, since the goal is to not have any non-volatile metal ions
Planar Lipid Bilayer Experiment平面脂双层实验
is diphytanoylphosphatidyl choline (DiphPC). It is prepared in the same method used for oxidized cholesterol (dried down a 2% solution, resuspend in decane and n-butanol to yield the desired %). There are small vials with 2mg/vial DiphPC in freezer. These were originally
SECTIONS 4µm paraffin wax sections SOLUTIONS 1. STOCK ALCOHOLIC SALT SOLUTION --Saturated sodium chloride in 80% alcohol 2. WORKING SOLUTION --Stock solution (1) 50cm3 --1% Sodium hydroxide 0.5cm3 --Mix, filter
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