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文献和实验Characterization of Neuropeptide Y (NPY) Receptors
. Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [125I][Leu31,Pro34]peptide YY and [125I]peptide YY3‐36 as selective Y1 and Y2 radioligands. J. Pharmacol. Exper. Ther. 272:673‐680.
Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization
two and seven (1 ). One of the sequences identified encoded the partial sequence of a novel protein most closely related to the type 1 neuropeptide Y (NPY) receptor, the only member of the NPY receptor family characterized by molecular cloning at that time
(2 ). This receptor is PYY preferring since it binds the intestinal hormone PYY (3 ) with high affinity and neuropeptide Y (NPY) (3 ) with a 5–10-fold lower affinity (1 –3 ). PYY and NPY trigger several biological effects through interaction with PYY receptors
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