Cre Recombinase Expression Pla

Regulation of Cre Recombinase: Use of Ligand-Regulated and Dimerizable Cre for Transgenesis

or, if combined with the use of a specific promoter, in a time- and cell-type-dependent manner. The most widely used approach to obtain this regulation relies on the fusion of the recombinase, mostly Cre recombinase, with the ligand-binding domain (LBD

Conditional Targeting: Inducible Deletion by Cre Recombinase

Tissue specific gene knockouts using Cre recombinase can have broad applicability in murine disease models of cardiovascular disease. The Cre system has been shown to have broad experimental versatility for both temporal and spatial control

Creation and Use of a Cre Recombinase Transgenic Database

. In addition, mammalian genetic determination often utilizes gene families, in which the members have similar structure and overlapping expression and functions. These two phenomena pointed out some limitations of the gene-targeting approach. In many cases