PC-3 Human prostate cancer cel

Animal Models of Prostate Cancer

, and human and animal prostates differ in their anatomy, cellular content, and in the development of spontaneous benign hyper-plasia that commonly occurs in men as they age but rarely in other species. Existing prostate cancer models include rodent models

Isolation and Culture of Prostate Cancer Cell Lines

. A procedure to propagate human prostatic epithelial cells in vitro for a limited number of cell generations was developed by others (1 ,2 ) and was extended to prostate cancer cells from primary tumors (1 ,3 ). However, reproducible methods to propagate

Immunocytochemical Detection and Characterization of Individual Micrometastatic Tumor Cells

for immunocytochemistry are described in detail in Chapter 2 by Brooks. Several studies have shown that bone marrow is an important, clinically relevant indicator organ for early disseminated cancer cells derived from various epithelial organs, including breast, lung