别 名:B2M; Beta 2 microglobulin precursor; Beta-2 Microglobulin; Beta chain of mhc class 1 proteins; Hdcma22p; B2MG_HUMAN; Beta 2 microglobin; Beta 2 microglobulin precursor; Beta chain of mhc class 1 proteins; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; CDABP0092.
货号:YLK-KT0139
分 子 量:12kDa
细胞定位:分泌型蛋白
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍:该基因编码一种与几乎所有有核细胞表面上的主要组织相容性复合体 (MHC) I 类重链相关的血清蛋白。 该蛋白质具有主要的 β 折叠片结构,可在某些病理条件下形成淀粉样蛋白原纤维。 该基因的突变已被证明会导致高分解代谢性低蛋白血症。
Subunit: Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis.
Subcellular Location: Secreted. Detected in serum and urine.
Post-translational modifications: Glycation of Ile-21 is observed in long-term hemodialysis patients.