Anti-IDE Monoclonal Antibody

产品简介

单位	支
英文名称	Anti-IDE Monoclonal Antibody
别名	IDE;INSULYSIN
宿主	Mouse
稀释比例	WB 1:1000-3000. IHC 1:100-300.
Gene ID	3416
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P14735
蛋白分子量	54/118kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm Cell membrane
免疫原	Synthetic Peptide
亚型	IgG1
纯化方法	Affinity purification
克隆号	3H4
背景资料	This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
克隆类型	Monoclonal Antibody
交叉反应	Human
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Immunohistochemistry of paraffin-embedded Human stomach cancer with IDE antibody diluted at 1:200

Western blot analysis with IDE antibody diluted at 1:2000;Lane: Hela