Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Cytoplasm Nucleus
免疫原
Recombinant protein of human SENP2
亚型
IgG
纯化方法
Affinity purification
背景资料
Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB.
Public Immunogen Range
40-380aa
克隆类型
Polyclonal Antibody
交叉反应
Human;Mouse;Rat
应用
WB;IHC
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with SENP2 antibody diluted at 1:2000;Lane: Mouse brain,Rat brain
Immunohistochemistry of paraffin-embedded Human breast cancer with SENP2 antibody diluted at 1:50