Anti-IGHG2 Polyclonal Antibody

Anti-IGHG2 Polyclonal Antibody



产品简介

靶标	IGHG2
别名	Immunoglobulin heavy constant gamma 2;Ig gamma-2 chain C region;Ig gamma-2 chain C region DOT;Ig gamma-2 chain C region TIL;Ig gamma-2 chain C region ZIE
宿主	Rabbit
稀释比例	WB 1:1000-3000.;IHC 1:50-200.
Gene ID	3501
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P01859
蛋白分子量	40kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cell membrane Secreted
免疫原	Recombinant protein of human IGHG2
亚型	IgG
纯化方法	Affinity purification
背景资料	Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Public Immunogen Range	124-459aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	WB;IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图


Western blot analysis with IGHG2 antibody diluted at 1:2000;Lane:Human IgG

Immunohistochemistry of paraffin-embedded Human tonsil with IGHG2 antibody diluted at 1:80.