Anti-CDH8 Polyclonal Antibody

Anti-CDH8 Polyclonal Antibody



产品简介

靶标	CDH8
别名	CDH8;Nbla04261
宿主	Rabbit
稀释比例	IHC 1:50-200.
Gene ID	1006
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P55286
蛋白分子量	88kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cell membrane Secreted
免疫原	A synthetic peptide of human CDH8
亚型	IgG
纯化方法	Affinity purification
背景资料	This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Public Immunogen Range	140-190/799aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human breast cancer with CDH8 antibody diluted at 1:100.

Immunohistochemistry of paraffin-embedded Human colorectal cancer with CDH8 antibody diluted at 1:100.