Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
免疫原
Recombinant protein of SARS-CoV/CoV-2 Spike S1
亚型
IgG
纯化方法
Affinity purification
背景资料
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with SARS-CoV/CoV-2 Spike S1 antibody diluted at 1:2000;Lane:SARS-CoV Spike S1,SARS-CoV-2 Spike RBD-28a,SARS-