Anti-INDO Polyclonal Antibody

产品简介

英文名称	Anti-INDO Polyclonal Antibody
靶标	PISD
别名	IDO;IDO-1;INDO;indoleamine 2
宿主	Rabbit
稀释比例	WB 1:1000-3000.
Gene ID	3620
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P14902
蛋白分子量	45kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	Recombinant protein of human INDO
亚型	IgG
纯化方法	Affinity purification
背景资料	Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity. Limits the growth of intracellular pathogens by depriving tryptophan. Protects the fetus from maternal immune rejection.
Public Immunogen Range	61-404aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with INDO antibody diluted at 1:2000;Lane:SKOV3