Anti-NUS1 Polyclonal Antibody

Anti-NUS1 Polyclonal Antibody



产品简介

英文名称	Anti-NUS1 Polyclonal Antibody
别名	Nogo-B receptor;NgBR;C6orf68;Cis-prenyltransferase subunit NgBR;Dehydrodolichyl diphosphate synthase complex subunit NUS1;Nuclear undecaprenyl pyrophosphate synthase 1 homolog
宿主	Rabbit
稀释比例	IHC 1:100-300.
Gene ID	116150
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q96E22
蛋白分子量	33kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide ofHuman NUS1
亚型	IgG
纯化方法	Affinity purification
背景资料	With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
Public Immunogen Range	140-190/293aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human melanoma with NUS1 antibody diluted at 1:200