Anti-DYRK1B Polyclonal Antibod

Anti-DYRK1B Polyclonal Antibody



产品简介

英文名称	Anti-DYRK1B Polyclonal Antibody
别名	MIRK
宿主	Rabbit
稀释比例	WB 1:1000-3000. IHC 1:100-300.
Gene ID	9149
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9Y463
蛋白分子量	69/66/65kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Nucleus
免疫原	A synthetic peptide of human DYRK1B
亚型	IgG
纯化方法	Octanoic acid-ammonium sulfate precipitation
背景资料	Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
Public Immunogen Range	330-380/629aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with DYRK1B antibody diluted at 1:2000;Lane: SH-SY5Y,MCF7,Jurkat,C2C12,Mouse testis

Immunohistochemistry of paraffin-embedded Human prostate cancer with DYRK1B antibody diluted at 1:200

Immunohistochemistry of paraffin-embedded Human thyroid cancer with DYRK1B antibody diluted at 1:200