Anti-RRM2B Polyclonal Antibody

Anti-RRM2B Polyclonal Antibody

产品简介

英文名称	Anti-RRM2B Polyclonal Antibody
别名	MTDPS8A;MTDPS8B;P53R2
宿主	Rabbit
稀释比例	WB 1:1000-3000. IHC 1:50-200.
Gene ID	50484
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q7LG56
蛋白分子量	5/8/16/35/40/49kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of Human RRM2B
亚型	IgG
性状	liquid
纯化方法	Affinity purification
背景资料	This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Public Immunogen Range	15-65/351aa
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human colorectal cancer with RRM2B antibody diluted at 1:100

Western blot analysis with RRM2B antibody diluted at 1:2000;Lane: Mouse brain