储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍:该基因编码的蛋白质属于利钠肽家族。 利钠肽与细胞外液体积和电解质稳态的控制有关。 这种蛋白质被合成为一个大的前体(包含一个信号肽),它被加工成从 N 端释放一个与血管活性肽相似的肽、心脏扩张肽和另一个从 C 端释放的具有利钠利尿活性的肽。 该基因的突变与家族性 6 型心房颤动有关。
Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.