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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
63
- 靶点:
/
- 级别:
科研
- 目录编号:
KT0736
- 克隆性:
多克隆
- 抗原来源:
/
- 保质期:
1年
- 抗体英文名:
phospho-ADRB2 (Ser346)
- 抗体名:
Rabbit Anti-phospho-ADRB2 (Ser346) antibody
- 标记物:
详询
- 宿主:
兔
- 适应物种:
Human, Rat, (predicted: Mouse, Dog, Horse, Sheep, )
- 免疫原:
KLH conjugated Synthesised phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346: RS(p-S)LK
- 亚型:
IgG
- 形态:
Liquid
- 应用范围:
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
50ul
中文名称:磷酸化肾上/腺素能受体β2抗体
英文名称:phospho-ADRB2 (Ser346)
别 名:β2-adrenergic receptor; ADRB2; ADRB2R; ADRBR; Adrenergic beta 2 receptor surface; B2AR; BAR; beta 2 adrenoceptor; Beta 2 adrenoreceptor; BETA2AR; Catecholamine receptor; beta2-adrenergic receptor; ADRB2_HUMAN.
货号:YLK-KT0735
分 子 量:46kDa
细胞定位:细胞浆 细胞膜
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Function:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Subunit:
Binds SLC9A3R1 and GPRASP1. Interacts with ARRB1 and ARRB2. Interacts with SRC, USP20 and USP33. Interacts with VHL; the interaction, which is increased on hydroxylation of ADRB2, ubiquitinates ADRB2 leading to its degradation. Interacts with EGLN3; the interaction hydroxylates ADRB2 facilitating VHL-E3 ligase-mediated ubiquitination.
注意:
所提供的本产品仅供研究使用,不得用于人类、治疗或诊断应用。


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