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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2766385-92-4
- 规格：
10 mM * 1 mL/1 mg/5 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥4400.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥1818.0 |
| 规格： | 5 mg | 产品价格： | ￥4000.0 |
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TMX-4113
CAS No. : 2766385-92-4
MCE 国际站：TMX-4113
产品活性：TMX-4113 是磷酸二酯酶 6D (PDE6D) 和酪蛋白激酶 1α (CK1α) 的降解剂。TMX-4113 可用于癌症研究。
研究领域：Metabolic Enzyme/Protease | Stem Cell/Wnt | Cell Cycle/DNA Damage | PROTAC
作用靶点：Phosphodiesterase (PDE) | Casein Kinase | Molecular Glues
In Vitro: TMX-4113 (compound 21; 1 μM; 4 h) shows a high degradation preference for PDE6D and CK1α in MOLT4 cells.
TMX-4113 (0 nM, 40 nM, 200 nM, 1µM; 4h) induces degradation of PDE6D in MOLT4 cells.
TMX-4113 (0 nM, 40 nM, 200 nM, 1µM; 4h) degrades over 50% of CK1α at a dose of 40 nM in MM.1S cells.
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