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- 保存条件：
Solution, -20°C, 2 years
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
2692624-22-7
- 规格：
500 μg (2.47 mM * 500 μL in Methanol)///1 mg///5 mg
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Ceramide C6-d7
CAS No. : 2692624-22-7
MCE 国际站：Ceramide C6-d7
产品活性：Ceramide C6-d7 是 Ceramide C6 的氘代物。Ceramide C6 是神经酰胺途径激活剂，是一种外源性短链神经酰胺，可诱导多种癌细胞凋亡。
作用靶点：Isotope-Labeled Compounds | Apoptosis
In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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文献和实验（神经）鞘脂类共有的结构单位。脂肪酸在鞘氨醇的氨基上具有酸酰胺键的结构。在其上如果结合糖，就成为鞘糖脂类，如果结合磷酸胆碱，就成为（神经）鞘磷脂。神经酰胺是鞘脂类的中间代谢产物，尤其在生物合成上占有重要的位置。在血小板以外仅少量存在。患有遗传性脂类积蓄症（lipidosis）之一的Fabry病的病人在小脑、肾脏中积蓄着大量神经酰胺。
Sphingomyelin and Ceramide Mass Assay
As described in Chapter 19 , a demonstration of changes in sphingomyelin (SM) and ceramide cellular contents (in response to regulatory molecules and/or other stimuli) is essential to stablish their involvement in the signaling proccess
Ceramide and Sphingosine-1-Phosphate Signaling in Embryonic Stem Cell Differentiation
Recent studies show that bioactive lipids are important regulators for stem cell survival and differentiation. The sphingolipid ceramide and its derivative, sphingosine-1-phosphate (S1P), can act synergistically on embryonic stem (ES) cell
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