通用注释 亚单元:Homotrimers of alpha 1(XVII)chains. Interacts (via cytoplasmic region) with ITGB4 (via cytoplasmic region). Interacts (via cytoplasmic region) with DST isoform 3 (via N-terminus). Interacts (via N-terminus) with PLEC. Interacts (via cytoplasmic region) with DSP.
功能:The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.
亚细胞位置: 97 kDa linear IgA disease antigen Secreted Extracellular space Extracellular matrix Basement membrane Localized in the lamina lucida beneath the hemidesmosomes.