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- 详细信息
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
63
- 靶点:
/
- 级别:
科研
- 目录编号:
KT0496
- 克隆性:
多克隆
- 抗原来源:
/
- 保质期:
1年
- 抗体英文名:
phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)
- 抗体名:
Rabbit Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312) antibody
- 标记物:
详询
- 宿主:
兔
- 适应物种:
Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
- 免疫原:
KLH conjugated Synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr315: PE(p-Y)LA
- 亚型:
IgG
- 形态:
Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
50ul
中文名称:磷酸化蛋白激酶AKT1,2,3抗体
英文名称:phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)
别 名:phospho-AKT1/AKT2/AKT3 (Tyr315+Tyr316+Tyr312); AKT1/AKT2/AKT3(phospho-Tyr315/316/312); AKT1/2/3 (phospho Y315 + Y316 + Y312); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; AKT 2; AKT2; AKT-2; AKT2_HUMAN; AKT 3; AKT3; AKT-3; AKT3_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PKB beta; PKB gamma; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.
货号:YLK-KT0496
分 子 量:56kDa
细胞定位:细胞核 细胞浆 细胞膜
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Subunit:
Interacts (via the C-terminus) with CCDC88A (via its C-terminus). Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding. Interacts with AGAP2 (isoform 2/PIKE-A); the interaction occurs in the presence of guanine nucleotides. Interacts with AKTIP. Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CDKN1B; the interaction phosphorylates CDKN1B promoting 14-3-3 binding and cell-cycle progression. Interacts with MAP3K5 and TRAF6. Interacts with BAD, PPP2R5B, STK3 and STK4. Interacts (via PH domain) with SIRT1. Interacts with SRPK2 in a phosphorylation-dependent manner. Interacts with RAF1. Interacts with TRIM13; the interaction ubiquitinates AKT1 leading to its proteasomal degradation. Interacts with TNK2 and CLK2. Interacts (via the C-terminus) with THEM4 (via its C-terminus). Interacts with and phosphorylated by PDPK1.

注意:
所提供的本产品仅供研究使用,不得用于人类、治疗或诊断应用。


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