存储缓冲液:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:Cell Cycle
通用注释 亚单元:Interacts with SNX17 (By similarity). Interacts with IHH.
功能:Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
亚细胞位置: Membrane Multi-pass membrane protein