存储缓冲液:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:Signal Transduction
通用注释 亚单元:Interacts (via C-terminus) with KLB; this interaction is direct. Interacts with FGFR4.
功能:Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB.
亚细胞位置: Secreted
文献
1. Coagonist of GLP-1 and glucagon decreases liver inflammation and atherosclerosis in dyslipidemic condition
Auth: V Patel, A Joharapurkar, S Kshirsagar, et al.
From: Chemico-Biological Interactions
2. Balanced Coagonist of GLP-1 and Glucagon Receptors Corrects Dyslipidemia by Improving FGF21 Sensitivity in Hamster Model
Auth: V Patel, A Joharapurkar, S Kshirsagar, et al.