别 名:SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1.
货号:YLK-KT0407
分 子 量:105kDa
细胞定位:细胞膜 分泌型蛋白
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍:可以作为粘合剂分子,其基质结合和可溶性片段可能在血管生物学中发挥关键作用。
Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Subunit: Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3.
Subcellular Location: Secreted. Cell membrane.
Tissue Specificity: Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.