别 名:Chromosome associated polypeptide C; hCAP C; XCAP C homolog; CAP C; CAPC; SMC 4; SMC4; SMC4L1; Structural maintenance of chromosomes 4 like 1; SMC4_HUMAN.
货号:YLK-KT0363
分 子 量:47kDa
细胞定位:细胞核 细胞浆
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍:SMC4 是凝聚素复合物的核心成分,它是将间期染色质转化为有丝分裂样凝聚染色体所必需的。 缩合蛋白复合物可能在 I 型拓扑异构酶存在的情况下将正超螺旋引入松弛的 DNA,并在 II 型拓扑异构酶存在的情况下将带切口的 DNA 转化为正打结形式。
Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.