- ￥535
- 翌圣生物（Yeasen）
- 91102ES08
- 上海
- 2025年11月11日
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- 详细信息
- 技术资料
- 保质期：
有效期1年
- 保存条件：
-20℃至-80℃保存
- 供应商：
翌圣生物科技(上海)股份有限公司
- 库存：
大量
- 英文名：
Recombinant Human GM-CSF
- 规格：
5μg
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Human GM-CSF |
91102ES08 |
5 μg |
815.00 |
| 91102ES60 |
100 μg |
6815.00 |
|
| 91102ES76 |
500 μg |
20425.00 |
|
| 91102ES80 |
1 mg |
31625.00 |
Product Description
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a powerful growth and differentiation factor which acts on hematopoietic progenitor cells and also activates differentiated granulocytes and macrophages. The 22 kDa glycosylated GMCSF, similar to IL3 and IL5, is a cytokine with a core of four bundled alpha -helices. Mature human GMCSF shares 63%70% amino acid sequence identity with canine, feline, porcine, and rat GMCSF and 54% with mouse GMCSF. GM-CSF has been and is still widely used as an adjuvant in clinical trials of vaccination with autologous tumor cells, peptides and/or dendritic cells in a variety of human neoplasms. The effects of GM-CSF on HIV-1 replication in primary monocytes and macrophages, and in related cell lines, have demonstrated augmentation of HIV-1 expression in vitro.
Product Properties
| Synonyms |
Granulocyte/Macrophage Colony-Stimulating Factor, GM-CSF, CSF-2, MGI-1GM, Pluripoietin-α |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived human GM-CSF protein, Ala18-Glu144. |
| Molecular Weight |
Approximately 14.5 kDa. |
| AA Sequence |
APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD CWEPVQE |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 98% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/mL, corresponding to a specific activity of > 1.0 × 107 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220908
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