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- 详细信息
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
/
- 级别:
科研
- 目录编号:
KT0243
- 克隆性:
多克隆
- 抗原来源:
/
- 保质期:
1年
- 抗体英文名:
SKA3
- 抗体名:
Rabbit Anti-SKA3 antibody
- 标记物:
详询
- 宿主:
兔
- 适应物种:
Rat, (predicted: Human, Mouse, Chicken, Cow, Horse, Rabbit, Sheep, )
- 免疫原:
KLH conjugated synthetic peptide derived from human SKA3: 201-300/412
- 亚型:
IgG
- 形态:
Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
中文名称:纺锤体和着丝粒相关蛋白3抗体
英文名称:SKA3
别 名:C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3.
货号:YLK-KT0243
分 子 量:46kDa
细胞定位:细胞核 细胞浆
纯化方法:affinity purified by Protein A
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

产品介绍:SKA1 复合体的组成部分,是外部动粒的微管结合亚复合体,对于正确的染色体分离至关重要。 SKA1 复合物是动粒-微管界面的直接组成部分,并作为寡聚体直接与微管结合。 该复合物以解聚耦合的方式促进微球沿微管的持续运动。 在复合物中,它介导微管刺激的寡聚化。

Function:
Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. The SKA1 complex is a direct component ofthe kinetochore-microtubule interface and directly associates withmicrotubules as oligomeric assemblies. The complex facilitates theprocessive movement of microspheres along a microtubule in adepolymerization-coupled manner. In the complex, it mediates themicrotubule-stimulated oligomerization.
Subunit:
Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1.

注意:
所提供的本产品仅供研究使用,不得用于人类、治疗或诊断应用。


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