晚期糖基化终末产物AGEs蛋白

中文名称：晚期糖基化终末产物AGEs蛋白

英文名称：AGEs

别    名：

分 子 量：


性    状：Lyophilized or Liquid

产品来源：提取

种属同源：N/A

纯化方法：

分类：天然蛋白

产品应用：BioloChIPl activity Immunology research 

保存条件：Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.




产品介绍：Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers who first described them. (The literature is inconsistent in applying these terms. For example, Maillard reaction products are sometimes considered intermediates and sometimes end products.) Side products generated in intermediate steps may be oxidizing agents (such as hydrogen peroxide), or not (such as beta amyloid proteins).[1] "Glycosylation" is sometimes used for "glycation" in the literature, usually as 'non-enzymatic glycosylation. The AGE modified BSA was produced by reacting BSA with glycolaldehyde under sterile conditions followed by extensive dialysis and purification steps.
AGEs又称非酶糖基化终末产物(AGEs) 是蛋白质、脂质和核酸等大分子的游离氨基与还原性单糖的醛基反应所生成的稳定的共价化合物, 在体内的积累、增多是导致糖尿病等多种疾病及其并发症的关键因素。AGEs的异常增多，可直接或间接地对机体产生致病作用。


提示：
所提供的本产品仅供研究使用，不得用于人类、治疗或诊断应用。