别名:High mobility group protein 1,HMG-1,Hmg-1,Hmg1
灵敏度:0.082ng/mL
特异性: Natural and recombinant Mouse High mobility group protein B1
研究领域:RNA Binding Protein(RBP)
精密度
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤7.1%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤9.2%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。
Sample Type |
Average(%) |
Recovery Range(%) |
Serum |
102 |
96-108 |
Plasma |
104 |
98-110 |
线性
给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。
Sample |
1:2 |
1:4 |
1:8 |
1:16 |
serum(n=5) |
87-97% |
91-100% |
91-99% |
102-112% |
EDTA plasma(n=5) |
100-111% |
106-114% |
95-107% |
91-103% |
heparin plasma(n=5) |
99-108% |
108-117% |
88-101% |
102-110% |
文献
1. HMGB1 released from GSDME-mediated pyroptotic epithelial cells participates in the tumorigenesis of colitis-associated colorectal cancer through the ERK1/2 pathway
Auth: G Tan, Cy Huang, Jy Chen, et al.
From: Journal of Hematology & Oncology
2. Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn’s disease by promoting intestinal inflammation
Auth: G Tan, Cy Huang, Jy Chen, et al.
From: Cell Reports
3. Radiosensitivity of colorectal cancer and radiation-induced gut damages are regulated by gasdermin E
Auth: G Tan, Cj Lin, Cy Huang, et al.
From: Cancer Letters
4. Simvastatin suppresses vascular inflammation and atherosclerosis in ApoEˉ/ˉ mice by downregulating the HMGB1-RAGE axis
Auth: M Liu, Y Yu, H Jiang, et al.
From: Acta Pharmacologica Sinica