此外,在专利和合作开发项目中,Nordic MUbio正在调查、测试和验证各种领域诊断应用的专利抗体和抗原。
Nordic was established in 1964 with a focus on immunology and holds over 1.700 specific antisera to human, mouse, monkey and rat immunoglobulin classes and their subclasses. Of interest may also be a wide range of polyclonal antisera to other serum proteins of different animal species and a unique series of polyclonal antisera against enzymes. Practically all antibodies are also offered as fluorescent and horseradish peroxidase conjugates as well as biotin conjugates for labels of the customers own choice. MUbio was created in 2000 and was spun out of Maastricht University in the Netherlands which gave rise to its name. Since its inception MUbio has developed 500 of its own products, many of which are exclusive clones available only to MUbio. On 4 February 2013, Nordic Immunological Laboratories BV acquired the assets of MUbio Products BV and in doing so changed its name to Nordic-MUbio. On 11th December 2013 Nordic-MUbio continued its rapid growth with the acquisition of the assets of An Der Grub Bio Research GmbH (ADG), extending the product range with Flow Cytometry products like the FIX&PERM® Cell Fixation and Permeabilization Kit. Nordic-MUbio has the ambition to become an important niche player in the following market segments: Monoclonal antibodies for Research Use Only Discovery and validation of new targets (biomarkers) with applications in diagnostic assays Ready-to-use tested flow cytometry antibodies with FIX&PERM®. Our products are all highly validated; over 80% of our antibodies are tested in immunohistochemistry on frozen tissues, almost 70% of our products have been testd in Flow Cytometry and over 50% are tested in Western Blot. Other applications include IHC on paraffin embedded tissues (40%), immunoprecipitation (15%) and immunofluorescence (6%). Our products are all highly validated; over 80% of our antibodies are tested in immunohistochemistry on frozen tissues, almost 70% of our products have been testd in Flow Cytometry and over 50% are tested in Western Blot. Other applications include IHC on paraffin embedded tissues (40%), immunoprecipitation (15%) and immunofluorescence (6%). Our antibodies target the following proteins: Antibodies directed toInterest fields AnnexinsApoptosis Cell adhesion moleculesCancer Cell cycle markersCardiovascular CD markersCell adhesion CytokinesCell cycle Cytoskeletal proteinsCell differentiation Extracellular matrix proteinsCell proliferation Filamentous phage proteinsCell signaling Haematology markersCytoskeleton HormonesImmunology Membrane proteinsNeurobiology Nuclear proteinsStem cell research Tumour markers Also, cross species reactivity is an important asset of Nordic-MUbio´s antibodies. In particular, Nordic-Mubio is offering antibodies to be used in the zebrafish model of the pharmaceutical R&D. Products are distributed worldwide through a selected number of distributors and OEM partners direct from Nordic-MUbio as the original producer. An important core competence of the company is to provide the right technical support, extensive scientific data, images, pictures and literature references for each individual product. In addition, in proprietary and partnered development programs Nordic-MUbio is investigating, testing and validating patented antibodies and antigens for diagnostic applications in various fields.